EMD-22454

Single-particle
4.4 Å
EMD-22454
3D View Gallery
Deposition: 14/08/2020
Map released: 09/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22454
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7jsh summary report (pdf.gz) Map and 7jsh FULL report (pdf.gz)
EMICSS annotations (xml)

Adeno-Associated Virus 2 Rep68 HD Heptamer-ssAAVS1 with ATPgS

EMD-22454

Single-particle
4.4 Å
EMD-22454
3D View Gallery
Deposition: 14/08/2020
Map released: 09/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Adeno-associated virus - 2, synthetic construct
Sample: Helicase domain heptamer of AAV-2 Rep68 complex bound to AAVS1 ssDNA.
Fitted models: 7jsh

Deposition Authors: Escalante CR
The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Santosh V, Musayev FN, Jaiswal R, Zarate-Perez F , Vandewinkel B , Dierckx C, Endicott M , Sharifi K, Dryden K, Henckaerts E, Escalante CR
(2020) Nucleic Acids Res , 48 , 12983 - 12999
PUBMED: 33270897
DOI: doi:10.1093/nar/gkaa1133
ISSN: 1362-4962
ASTM: NARHAD