EMDB EMD-22019

Single particle reconstruction
4.7Å resolution

Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed)

Map released:
Overview of EMD-22019
Source organisms:
Fitted atomic model: 6x36
Primary publication:
Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM
Woll KW, Haji-Ghassemi O, Van Petegem F
Nat Commun - (2021)

Function and Biology Details

Sample name: ryanodine receptor-FKBP1B-calmodulin complex
Proteins: ryanodine receptor-FKBP1B-calmodulin complex, ryanodine receptor, FKBP1B, Calmodulin, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, Calmodulin-1

Experimental Information Details

Resolution: 4.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: PHENIX
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)