EMDB EMD-21989

Single particle reconstruction
3.05Å resolution

Inward-facing state of the glutamate transporter homologue GltPh in complex with L-aspartate and sodium ions

Map released:
Last modified:
Overview of EMD-21989
Source organism: Pyrococcus horikoshii [53953]
Fitted atomic model: 6x15
Related EM entries by publication: EMD-21986, EMD-21987, EMD-21988, EMD-21990, EMD-21991
Primary publication:
Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters.
Wang X, Boudker O
Elife 9 - (2020)
PMID: 33155546

Function and Biology Details

Sample name: Complex of inward-facing state of GltPh with L-aspartate and sodium ions in MSP1E3 nanodisc
Ligands: SODIUM ION, ASPARTIC ACID, MERCURY (II) ION, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, water
Proteins: Complex of inward-facing state of GltPh with L-aspartate and sodium ions in MSP1E3 nanodisc, Glutamate transporter homologue GltPh

Experimental Information Details

Resolution: 3.05Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Microscope: FEI TITAN KRIOS
Detector: OTHER