EMDB EMD-21980

Single particle reconstruction
10.0Å resolution

Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin

Map released:
Overview of EMD-21980
Source organisms:
Fitted atomic model: 6x0n
Related EM entries by publication: EMD-21970, EMD-21971, EMD-21978, EMD-21979
Primary publication:
Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin
Bilokapic S, Suskiewicz MJ, Ahel I, Halic M
Nature - (2020)

Function and Biology Details

Sample name: Histone H3.2, Histone H4, Histone H2A type 1, Histone H2B 1.1, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2/DNA Complex
Nucleic acids: DNA (167-MER), DNA (167-MER)
Proteins: Histone H3.2, Histone H4, Histone H2A type 1, Histone H2B 1.1, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2/DNA Complex, Histone H3.2, Histone H4, Histone H2A type 1, Histone H2B 1.1, DNA, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2, Histone H3.2, Histone H4, Histone H2A, Histone H2B 1.1, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2

Experimental Information Details

Resolution: 10.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: OTHER