EMDB EMD-21978

Single particle reconstruction
3.9Å resolution

Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin

Map released:
Overview of EMD-21978
Source organisms:
Fitted atomic model: 6x0l
Related EM entries by publication: EMD-21970, EMD-21971, EMD-21979, EMD-21980
Primary publication:
Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin
Bilokapic S, Suskiewicz MJ, Ahel I, Halic M
Nature - (2020)

Function and Biology Details

Sample name: PARP2/HPF1
Nucleic acids: DNA (167-MER), DNA (167-MER)
Proteins: PARP2/HPF1, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2, DNA, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: OTHER