EMDB EMD-21967

Single particle reconstruction
4.0Å resolution

Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state.

Map released:
Last modified:
Overview of EMD-21967
Fitted atomic model: 6wyk
Primary publication:
Glutamate transporters have a chloride channel with two hydrophobic gates.
Chen I, Pant S, Wu Q, Cater RJ, Sobti M, Vandenberg RJ, Stewart AG, Tajkhorshid E, Font J, Ryan RM
Nature - (2021)
PMID: 33597752

Function and Biology Details

Sample name: Glutamate transporter homolog GltPh monomer in intermediate chloride conducting configuration
Ligand: ASPARTIC ACID
Proteins: Glutamate transporter homolog GltPh monomer in intermediate chloride conducting configuration, Glutamate transporter homolog

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: FEI FALCON III (4k x 4k)