EMDB EMD-21966

Single particle reconstruction
3.7Å resolution

Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate state

Map released:
Last modified:
Overview of EMD-21966
Fitted atomic model: 6wyj
Primary publication:
Glutamate transporters have a chloride channel with two hydrophobic gates.
Chen I, Pant S, Wu Q, Cater RJ, Sobti M, Vandenberg RJ, Stewart AG, Tajkhorshid E, Font J, Ryan RM
Nature - (2021)
PMID: 33597752

Function and Biology Details

Sample name: Monomer of Glutamate transporter homolog, GltPh, in intermediate configuration
Ligand: ASPARTIC ACID
Proteins: Monomer of Glutamate transporter homolog, GltPh, in intermediate configuration, Glutamate transporter homolog

Experimental Information Details

Resolution: 3.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: FEI FALCON III (4k x 4k)