EMDB EMD-21658

Single particle reconstruction
5.3Å resolution

Cryo-EM structure of human Cohesin-NIPBL-DNA complex

Map released:
Last modified:
Overview of EMD-21658
Source organism: Homo sapiens [9606]
Fitted atomic model: 6wg3
Related EM entry by publication: EMD-21663
Primary publication:
Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Shi Z, Gao H, Bai XC, Yu H
Science - (2020)
PMID: 32409525

Function and Biology Details

Sample name: Human Cohesin-NIPBL-DNA Complex
Ligand: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Nucleic acids: DNA (51-MER), DNA (51-MER)
Proteins: Human Cohesin-NIPBL-DNA Complex, Structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 3, Double-strand-break repair protein rad21 homolog, Cohesin subunit SA-1, Nipped-B-like protein

Experimental Information Details

Resolution: 5.3Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: OTHER