EMDB EMD-21501

Helical reconstruction
2.77Å resolution

Amyloid-beta(1-40) fibril derived from Alzheimer's disease cortical tissue

Map released:
Last modified:
Overview of EMD-21501
Source organism: Homo sapiens [9606]
Fitted atomic model: 6w0o
Primary publication:
Molecular structure of a prevalent amyloid-beta fibril polymorph from Alzheimer's disease brain tissue.
Ghosh U, Thurber KR, Yau WM, Tycko R
Proc.Natl.Acad.Sci.USA 118 - (2021)
PMID: 33431654

Function and Biology Details

Sample name: amyloid-beta(1-40) fibrils derived from human AD brain
Proteins: amyloid-beta(1-40) fibrils derived from human AD brain, Amyloid-beta precursor protein

Experimental Information Details

Resolution: 2.77Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: TFS KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)