EMD-21439

Single-particle
3.6 Å
EMD-21439
3D View Gallery
Deposition: 21/02/2020
Map released: 13/05/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21439
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Closed conformation of ABCG2 in the presence of mitoxantrone

EMD-21439

Single-particle
3.6 Å
EMD-21439
3D View Gallery
Deposition: 21/02/2020
Map released: 13/05/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ABCG2 reconstituted in lipid nanodisc

Deposition Authors: Orlando BJ, Maofu L
ABCG2 transports anticancer drugs via a closed-to-open switch.
Orlando BJ, Liao M
(2020) Nat Commun , 11 , 2264 - 2264
PUBMED: 32385283
DOI: doi:10.1038/s41467-020-16155-2
ISSN: 2041-1723
Grant Support: