EMDB EMD-21256

Single particle reconstruction
3.52Å resolution

BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2

Map released:
Overview of EMD-21256
Source organisms:
Fitted atomic model: 6vo0
Related EM entries by publication: EMD-21498, EMD-21499, EMD-21500
Primary publication:
HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, Ward AB
Sci Adv 6 eaba0512-eaba0512 (2020)
PMID: 32548265

Function and Biology Details

Sample name: BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Proteins: BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2, Fab 43A2, BG505 SOSIP.v5.2, 43A2 light chain, 43A2 heavy chain, Envelope glycoprotein gp120, Envelope glycoprotein gp41

Experimental Information Details

Resolution: 3.52Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)