EMDB EMD-21237

Single particle reconstruction
3.07Å resolution

Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-3)

Map released:
Last modified:
Overview of EMD-21237
Source organism: Danio rerio [7955]
Fitted atomic model: 6vm3
Related EM entries by publication: EMD-20714, EMD-20715, EMD-20731, EMD-21234, EMD-21236
Primary publication:
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.
Kumar A, Basak S, Rao S, Gicheru Y, Mayer ML, Sansom MSP, Chakrapani S
Nat Commun 11 3752-3752 (2020)
PMID: 32719334

Function and Biology Details

Sample name: Glycine receptor subunit alpha Z1
Ligands: GLYCINE, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
Proteins: Glycine receptor subunit alpha Z1, Glycine receptor subunit alphaZ1

Experimental Information Details

Resolution: 3.07Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C5
Reconstruction software: RELION
Detector: OTHER