EMDB EMD-21228

Single particle reconstruction
3.02Å resolution

Cryo-electron microscopy structures of a gonococcal multidrug efflux pump illuminate a mechanism of drug recognition with ampicillin

Map released:
Overview of EMD-21228
Source organism: Neisseria gonorrhoeae [485]
Fitted atomic model: 6vks
To be published

Function and Biology Details

Sample name: MtrD efflux pump
Ligands: PHOSPHATIDYLETHANOLAMINE, (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Proteins: MtrD efflux pump, Efflux pump membrane transporter

Experimental Information Details

Resolution: 3.02Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)