EMDB EMD-21041

Single particle reconstruction
2.97Å resolution

Structure of TrkH-TrkA in complex with ATP

Map released:
Overview of EMD-21041
Fitted atomic model: 6v4j
Primary publication:
TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential.
Zhang H, Pan Y, Hu L, Hudson MA, Hofstetter KS, Xu Z, Rong M, Wang Z, Prasad BVV, Lockless SW, Chiu W, Zhou M
Nat Commun 11 547-547 (2020)
PMID: 31992706

Function and Biology Details

Sample name: TrkH-TrkA
Proteins: TrkH-TrkA, Trk system potassium uptake protein TrkH, Potassium uptake protein TrkA

Experimental Information Details

Resolution: 2.97Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: JEOL 3200FSC
Detector: GATAN K2 SUMMIT (4k x 4k)