EMDB EMD-20850

Single particle reconstruction
4.5Å resolution

Focused map of type 3 IP3 receptor N-terminal domain revealing the presence of a self-binding peptide

Map released:
Last modified:
Overview of EMD-20850
Source organism: Homo sapiens [9606]
Related EM entry by publication: EMD-20849
Primary publication:
Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
Azumaya CM, Linton EA, Risener CJ, Nakagawa T, Karakas E
J.Biol.Chem. - (2020)
PMID: 31915246

Function and Biology Details

Sample name: inositol 1,4,5-triphosphate receptor, type 3
Proteins: inositol 1,4,5-triphosphate receptor, type 3, inositol 1,4,5-triphosphate receptor, type 3

Experimental Information Details

Resolution: 4.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: cisTEM
Microscope: FEI POLARA 300
Detector: GATAN K2 SUMMIT (4k x 4k)