EMDB EMD-20789

Single particle reconstruction
2.7Å resolution

Cryo-EM structure of human CALHM2 in a ruthenium red-bound inhibited state

Map released:
Last modified:
Overview of EMD-20789
Source organism: Homo sapiens [9606]
Fitted atomic model: 6uiw
Related EM entry by publication: EMD-20788, EMD-20790
Primary publication:
The structures and gating mechanism of human calcium homeostasis modulator 2.
Choi W, Clemente N, Sun W, Du J, Lu W
Nature - (2019)
PMID: 31776515

Function and Biology Details

Sample name: human CALHM2
Ligand: ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
Proteins: human CALHM2, Calcium homeostasis modulator protein 2

Experimental Information Details

Resolution: 2.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C11
Reconstruction software: RELION
Detector: GATAN K2 SUMMIT (4k x 4k)