EMD-20735
Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
EMD-20735
Single-particle4.2 Å
Deposition: 19/09/2019Map released: 02/10/2019
Last modified: 30/10/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: Complex of the CH235 unmutated common ancestor (UCA) bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
Fitted models: 6uda
Deposition Authors: Acharya P
Sample: Complex of the CH235 unmutated common ancestor (UCA) bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
Fitted models: 6uda
Deposition Authors: Acharya P
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche CC,
Henderson R,
Hsu A,
Behrens S ,
Chen X ,
Zhou T ,
Wiehe K,
Saunders KO ,
Alam SM,
Bonsignori M ,
Borgnia MJ ,
Sattentau QJ ,
Eaton A,
Greene K,
Gao H ,
Liao HX,
Williams WB,
Peacock J,
Tang H,
Perez LG,
Edwards RJ ,
Kepler TB ,
Korber BT,
Kwong PD ,
Mascola JR,
Acharya P ,
Haynes BF,
Montefiori DC
(2019) PLoS Pathog , 15 , e1008026 - e1008026
,
Chen X ,
Zhou T ,
Wiehe K,
Saunders KO ,
Alam SM,
Bonsignori M ,
Borgnia MJ ,
Sattentau QJ ,
Eaton A,
Greene K,
Gao H ,
Liao HX,
Williams WB,
Peacock J,
Tang H,
Perez LG,
Edwards RJ ,
Kepler TB ,
Korber BT,
Kwong PD ,
Mascola JR,
Acharya P ,
Haynes BF,
Montefiori DC
(2019) PLoS Pathog , 15 , e1008026 - e1008026
Grant Support: