EMDB EMD-20731

Single particle reconstruction
3.5Å resolution

Full length Glycine receptor reconstituted in lipid nanodisc in Gly/PTX-bound open/blocked conformation

Map released:
Overview of EMD-20731
Source organism: Danio rerio [7955]
Fitted atomic model: 6ud3
Primary publication:
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs
Kumar A, Basak S, Rao S, Gicheru YW, Mayer M, Sansom MS, Chakrapani S
Nat Commun - (2020)

Function and Biology Details

Sample name: Glycine receptor subunit alpha Z1
Ligands: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione
Proteins: Glycine receptor subunit alpha Z1, Glycine receptor subunit alphaZ1

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Detector: OTHER