EMD-20722

Single-particle
7.13 Å
EMD-20722
3D View Gallery
Deposition: 13/09/2019
Map released: 25/03/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20722

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human IMPDH2 treated with ATP and IMP. Fully extended filament segment reconstruction.

EMD-20722

Single-particle
7.13 Å
EMD-20722
3D View Gallery
Deposition: 13/09/2019
Map released: 25/03/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction.

Deposition Authors: Johnson MC, Kollman JM
Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation.
Johnson MC , Kollman JM
(2020) eLife , 9
PUBMED: 31999252
DOI: doi:10.7554/eLife.53243
ISSN: 2050-084X