EMDB EMD-20544

Single particle reconstruction
2.7Å resolution

MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine

Map released:
Last modified:
Overview of EMD-20544
Fitted atomic model: 6q06
Related EM entries by publication: EMD-20542, EMD-20543, EMD-20545, EMD-20829
Primary publication:
Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Park YJ, Walls AC, Wang Z, Sauer MM, Li W, Tortorici MA, Bosch BJ, DiMaio F, Veesler D
Nat.Struct.Mol.Biol. 26 1151-1157 (2019)
PMID: 31792450

Function and Biology Details

Sample name: MERS-CoV S ectodomain in complex with 5-N-acetyl neuraminic acid
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE, FOLIC ACID, O-SIALIC ACID, BETA-D-GALACTOSE, water
Proteins: MERS-CoV S ectodomain in complex with 5-N-acetyl neuraminic acid, Spike glycoprotein

Experimental Information Details

Resolution: 2.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)