EMDB EMD-20535

Single particle reconstruction
4.5Å resolution

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only

Map released:
Overview of EMD-20535
Source organism: Cricetus cricetus [10034]
Fitted atomic model: 6pzi
Related EM entries by publication: EMD-20528, EMD-20530, EMD-20533, EMD-20534
Primary publication:
Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Martin GM, Sung MW, Yang Z, Innes LM, Kandasamy B, David LL, Yoshioka C, Shyng SL
Elife 8 - (2019)
PMID: 31343405

Function and Biology Details

Sample name: SUR1
Ligand: ADENOSINE-5'-TRIPHOSPHATE
Proteins: SUR1, ATP-binding cassette sub-family C member 8

Experimental Information Details

Resolution: 4.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)