EMDB EMD-20500

Single particle reconstruction
4.5Å resolution

The HIV-1 Envelope Glycoprotein Clone BG505 SOSIP.664 in Complex with Three Copies of the Bovine Broadly Neutralizing Antibody, NC-Cow1, Fragment Antigen Binding Domain

Map released:
Last modified:
Overview of EMD-20500
Source organisms:
Fitted atomic model: 6pw6
Primary publication:
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Stanfield RL, Berndsen ZT, Huang R, Sok D, Warner G, Torres JL, Burton DR, Ward AB, Wilson IA, Smider VV
Sci Adv 6 eaba0468-eaba0468 (2020)
PMID: 32518821

Function and Biology Details

Sample name: A complex of the HIV-1 Envelope Glycoprotein clone BG505 SOSIP.664 and 3 copies of the bovine Fab NC-Cow1
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: A complex of the HIV-1 Envelope Glycoprotein clone BG505 SOSIP.664 and 3 copies of the bovine Fab NC-Cow1, Envelope Glycoprotein clone BG505 SOSIP.664, bovine Fab NC-Cow1, Envelope glycoprotein gp120, Envelope glycoprotein gp41, Broadly Neutralizing Antibody NC-Cow1 Heavy Chain

Experimental Information Details

Resolution: 4.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)