EMD-20490
Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001 in saposin nanodiscs
EMD-20490
Single-particle4.55 Å
Deposition: 19/07/2019Map released: 11/09/2019
Last modified: 23/11/2022
Sample Organism:
Homo sapiens
Sample: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Deposition Authors: Gharpure A
,
Teng J,
Zhuang Y ,
Noviello CM,
Walsh RM,
Cabuco R,
Howard RJ,
Zaveri NT ,
Lindahl E,
Hibbs RE
Sample: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Deposition Authors: Gharpure A
,
Teng J,
Zhuang Y ,
Noviello CM,
Walsh RM,
Cabuco R,
Howard RJ,
Zaveri NT ,
Lindahl E,
Hibbs RE
Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Gharpure A ,
Teng J,
Zhuang Y ,
Noviello CM,
Walsh Jr RM ,
Cabuco R,
Howard RJ,
Zaveri NT ,
Lindahl E,
Hibbs RE
(2019) Neuron , 104 , 501 - 511.e6
,
Teng J,
Zhuang Y ,
Noviello CM,
Walsh Jr RM ,
Cabuco R,
Howard RJ,
Zaveri NT ,
Lindahl E,
Hibbs RE
(2019) Neuron , 104 , 501 - 511.e6
Grant Support:
- Welch Foundation: I-1812 (United States)
- National Institutes of Health/National Institute on Drug Abuse: T32DA07290 (United States)
- National Institutes of Health/National Institute of General Medical Sciences: T32GM008203 (United States)
- National Institutes of Health/National Institute on Drug Abuse: DA037492 (United States)
- National Institutes of Health/National Institute on Drug Abuse: DA042072 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke: NS095899 (United States)