EMDB EMD-20181

Single particle reconstruction
3.0Å resolution

human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in non-canonical conformation (NC state)

Map released:
Overview of EMD-20181
Source organisms:
Fitted atomic model: 6osa
Related EM entry by publication: EMD-20180
Primary publication:
Conformational transitions of a neurotensin receptor 1-Gi1complex.
Kato HE, Zhang Y, Hu H, Suomivuori CM, Kadji FMN, Aoki J, Krishna Kumar K, Fonseca R, Hilger D, Huang W, Latorraca NR, Inoue A, Dror RO, Kobilka BK, Skiniotis G
Nature - (2019)
PMID: 31243364

Function and Biology Details

Sample name: hNTSR1-Gi1 complex in non-canonical conformation (NC state)
Proteins: hNTSR1-Gi1 complex in non-canonical conformation (NC state), Neurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

Experimental Information Details

Resolution: 3.0Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)