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EMD-20176
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
EMD-20176
Single-particle3.9 Å
Deposition: 30/04/2019Map released: 12/06/2019
Last modified: 20/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta
Sample: Complex of RC1 variant of BG505 SOSIP.664 trimer with three elicted Ab874NHP Fabs and three human bNAb 8ANC195 Fabs
Fitted models: 6oro
Deposition Authors: Abernathy ME, Gristick HB
Sample: Complex of RC1 variant of BG505 SOSIP.664 trimer with three elicted Ab874NHP Fabs and three human bNAb 8ANC195 Fabs
Fitted models: 6oro
Deposition Authors: Abernathy ME, Gristick HB
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Escolano A,
Gristick HB,
Abernathy ME,
Merkenschlager J,
Gautam R,
Oliveira TY 
,
Pai J ,
West Jr AP,
Barnes CO ,
Cohen AA,
Wang H,
Golijanin J,
Yost D,
Keeffe JR,
Wang Z,
Zhao P ,
Yao KH,
Bauer J ,
Nogueira L,
Gao H,
Voll AV,
Montefiori DC,
Seaman MS,
Gazumyan A,
Silva M,
McGuire AT,
Stamatatos L,
Irvine DJ,
Wells L ,
Martin MA,
Bjorkman PJ,
Nussenzweig MC
(2019) Nature , 570 , 468 - 473
,
Pai J ,
West Jr AP,
Barnes CO ,
Cohen AA,
Wang H,
Golijanin J,
Yost D,
Keeffe JR,
Wang Z,
Zhao P ,
Yao KH,
Bauer J ,
Nogueira L,
Gao H,
Voll AV,
Montefiori DC,
Seaman MS,
Gazumyan A,
Silva M,
McGuire AT,
Stamatatos L,
Irvine DJ,
Wells L ,
Martin MA,
Bjorkman PJ,
Nussenzweig MC
(2019) Nature , 570 , 468 - 473