EMD-19844

Single-particle
3.2 Å
EMD-19844
3D View Gallery
Deposition: 14/03/2024
Map released: 29/01/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19844
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9eo1 summary report (pdf.gz) Map and 9eo1 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo_EM structure of human FAN1 in complex with 5' flap DNA substrate

EMD-19844

Single-particle
3.2 Å
EMD-19844
3D View Gallery
Deposition: 14/03/2024
Map released: 29/01/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: FAN1-DNA complex
Fitted models: 9eo1

Deposition Authors: Jeyasankar G , Salerno-Kochan A , Thomsen M
A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA.
Aretz J , Jeyasankar G , Salerno-Kochan A , Thomsen M, Thieulin-Pardo G, Haque T , Monteagudo E, Felsenfeld D, Finley M , Vogt TF, Boudet J , Prasad BC
(2025) Nat Commun , 16 , 4412 - 4412
PUBMED: 40368883
DOI: doi:10.1038/s41467-025-59324-x
ISSN: 2041-1723
Grant Support: