EMD-19625
H. sapiens MCM double hexamer containing the MCM5 R195A/L209G mutant
EMD-19625
Single-particle5.6 Å
Deposition: 13/02/2024Map released: 02/10/2024
Last modified: 25/12/2024
Sample Organism:
Homo sapiens
Sample: H. sapiens MCM double hexamer containing the MCM5 R195A/L209G mutant
Deposition Authors: Puehringer T
,
Weissmann F ,
Greiwe J ,
Diffley JFX ,
Costa A
Sample: H. sapiens MCM double hexamer containing the MCM5 R195A/L209G mutant
Deposition Authors: Puehringer T
,
Weissmann F ,
Greiwe J ,
Diffley JFX ,
Costa A
MCM double hexamer loading visualized with human proteins.
Weissmann F ,
Greiwe JF ,
Puhringer T ,
Eastwood EL ,
Couves EC ,
Miller TCR ,
Diffley JFX ,
Costa A
(2024) Nature , 636 , 499 - 508
,
Greiwe JF ,
Puhringer T ,
Eastwood EL ,
Couves EC ,
Miller TCR ,
Diffley JFX ,
Costa A
(2024) Nature , 636 , 499 - 508
Secondary citations:
- Weissmann F, Greiwe JF, Puhringer T, Miller TCR, Diffley JFX & Costa A. (2024) MCM Double Hexamer Loading Visualised with Human Proteins. bioRxiv,
- Liebschner D, Afonine PV, Baker ML, Bunkoczi G, Chen VB, Croll TI, Hintze B, Hung LW, Jain S, McCoy AJ, Moriarty NW, Oeffner RD, Poon BK, Prisant MG, Read RJ, Richardson JS, Richardson DC, Sammito MD, Sobolev OV, Stockwell DH, Terwilliger TC, Urzhumtsev AG, Videau LL, Williams CJ & Adams PD. (2019) Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix. Acta Crystallogr D Struct Biol, 75, 861 - 877
Grant Support:
- The Francis Crick Institute: CC2002, CC2009 (United Kingdom)
- European Research Council (ERC): 820102 (European Union)
- Boehringer Ingelheim Fonds (BIF): (Germany)
- Wellcome Trust: 219527/Z/19/Z (United Kingdom)
- European Research Council (ERC): 101020432-MeChroRep (European Union)