EMD-19110

Single-particle
2.98 Å
EMD-19110
3D View Gallery
Deposition: 12/12/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19110
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8rew summary report (pdf.gz) Map and 8rew FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of human GARP-lTGFbeta1 in complex with a Fab fragment derived from an activating antibody.

EMD-19110

Single-particle
2.98 Å
EMD-19110
3D View Gallery
Deposition: 12/12/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: human GAPR-lTGFbeta1 in complex with Fab LHT-22.
Fitted models: 8rew

Deposition Authors: Felix J , Lambert F , Marien L , van der Woning B , Savvides SN , Lucas S
Antibody-mediated TGF-beta 1 activation for the treatment of diseases caused by deleterious T cell activity.
Lambert F , Felix J , Wautier S , Dupre E , Jamez M, Michiels C, Gaignage M , Marien L , Lesage M , van der Woning B , Savvides SN , Lucas S
(2025) Cell Rep , 44 , 116061 - 116061
PUBMED: 40742810
DOI: doi:10.1016/j.celrep.2025.116061
ISSN: 2211-1247