EMD-19066

Single-particle
7.37 Å
EMD-19066
3D View Gallery
Deposition: 07/12/2023
Map released: 29/05/2024
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19066

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TREK2 in OGNG/CHS detergent micelle with biparatopic inhibitory nanobody Nb6158

EMD-19066

Single-particle
7.37 Å
EMD-19066
3D View Gallery
Deposition: 07/12/2023
Map released: 29/05/2024
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Complex of TREK2 and inhibitory nanobody Nb6158

Deposition Authors: Smith KHM , Tucker SJ
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Rodstrom KEJ, Cloake A, Sormann J , Baronina A, Smith KHM , Pike ACW , Ang J, Proks P, Schewe M , Holland-Kaye I, Bushell SR, Elliott J , Pardon E , Baukrowitz T, Owens RJ , Newstead S , Steyaert J , Carpenter EP, Tucker SJ
(2024) Nat Commun , 15 , 4173 - 4173
PUBMED: 38755204
DOI: doi:10.1038/s41467-024-48536-2
ISSN: 2041-1723
Grant Support: