EMD-19031
CryoEM structure of primed myosin-5a (ADP-Pi state)
EMD-19031
Single-particle4.9 Å
Deposition: 04/12/2023Map released: 11/12/2024
Last modified: 25/06/2025
Sample Organism:
Mus musculus
Sample: Unconventional myosin-5a
Fitted models: 8rbg
Deposition Authors: Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M
,
Winkelmann DA,
Sobott F ,
Galkin VE ,
Knight PJ ,
Muench SP ,
Scarff CA ,
White HD
Sample: Unconventional myosin-5a
Fitted models: 8rbg
Deposition Authors: Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M
,
Winkelmann DA,
Sobott F ,
Galkin VE ,
Knight PJ ,
Muench SP ,
Scarff CA ,
White HD
Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM.
Klebl DP,
McMillan SN,
Risi C,
Forgacs E,
Virok B,
Atherton JL,
Harris SA,
Stofella M ,
Winkelmann DA,
Sobott F ,
Galkin VE ,
Knight PJ ,
Muench SP ,
Scarff CA ,
White HD
(2025) Nature , 642 , 519 - 526
,
Winkelmann DA,
Sobott F ,
Galkin VE ,
Knight PJ ,
Muench SP ,
Scarff CA ,
White HD
(2025) Nature , 642 , 519 - 526
Grant Support:
- Wellcome Trust: (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): (United Kingdom)
- American Heart Association: (United States)
- Medical Research Council (MRC, United Kingdom): (United Kingdom)
- British Heart Foundation: (United Kingdom)