EMD-18992

Single-particle
3.12 Å
EMD-18992
3D View Gallery
Deposition: 27/11/2023
Map released: 30/10/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18992
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8r7v summary report (pdf.gz) Map and 8r7v FULL report (pdf.gz)
EMICSS annotations (xml)

MutSbeta bound to compound CHDI-00898647 in the canonical DNA-mismatch bound form

EMD-18992

Single-particle
3.12 Å
EMD-18992
3D View Gallery
Deposition: 27/11/2023
Map released: 30/10/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: MutSbeta in complex with the mismatched DNA and compound
Fitted models: 8r7v

Deposition Authors: Haque T, Brace G, Felsenfeld D, Tilack K, Schaertl S, Ballantyne G, Maillard M, Iyer R, Prasad B, Thomsen M, Wilkionson H, Plotnikov N, Ritzefeld M

Identification of orthosteric inhibitors of MutSbeta ATPase function
Haque T, Brace G
To Be Published
Grant Support: