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EMD-18774

Single-particle
3.29 Å
EMD-18774
3D View Gallery
Deposition: 26/10/2023
Map released: 06/12/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18774
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8qzc summary report (pdf.gz) Map and 8qzc FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM map of calcium-bound mTMEM16A(ac)-L647V/I733V chloride channel at 3.29 A resolution

EMD-18774

Single-particle
3.29 Å
EMD-18774
3D View Gallery
Deposition: 26/10/2023
Map released: 06/12/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: mouse TMEM16A ac splice variant with introduced mutations L647V and I733V in complex with calcium
Fitted models: 8qzc

Deposition Authors: Lam AKM , Dutzler R , Dutzler R
Mechanistic basis of ligand efficacy in the calcium-activated chloride channel TMEM16A.
Lam AK, Dutzler R
(2023) EMBO J , 42 , e115030 - e115030
PUBMED: 37984335
DOI: doi:10.15252/embj.2023115030
ISSN: 1460-2075
ASTM: EMJODG
Grant Support:
  • European Research Council (ERC): 339116 (European Union)
  • University of Zurich: FK-18-048 (Switzerland)
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