EMD-18672

Helical reconstruction
4.07 Å
EMD-18672
3D View Gallery
Deposition: 18/10/2023
Map released: 21/05/2025
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18672

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8qvq summary report (pdf.gz) Map-8qvq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S29P, polymorph 2

EMD-18672

Helical reconstruction
4.07 Å
EMD-18672
3D View Gallery
Deposition: 18/10/2023
Map released: 21/05/2025
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human islet amyloid polypeptide (hIAPP)
Fitted models: 8qvq

Deposition Authors: Ooi SA, Valli D, Maj M
Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics.
Ooi SA, Valli D, Kuska MI , Mari H, Chaudhary H, Wahlgren WY, Westenhoff S, Tietze AA, Novials A, Servitja JM, Maj M
(2025) J Mol Biol , 437 , 169405 - 169405
PUBMED: 40850490
DOI: doi:10.1016/j.jmb.2025.169405
ISSN: 1089-8638
ASTM: JMOBAK