EMD-17730
masked refinement giving rise to better defined protruding densities of the potential macrodomain outside the AUD helical assemblies.
EMD-17730
Helical reconstruction2.98 Å
Deposition: 25/06/2023Map released: 10/07/2024
Last modified: 22/01/2025
Sample Organism:
Chikungunya virus strain S27-African prototype
Sample: Helical scaffold assembly of CHIKV nsP3 mediated by its Unique alphavirus domain.
Deposition Authors: Reguera J
,
Hons M ,
Zimberger C ,
Ptchelkine D,
Jones R ,
Desfosses A
Sample: Helical scaffold assembly of CHIKV nsP3 mediated by its Unique alphavirus domain.
Deposition Authors: Reguera J
,
Hons M ,
Zimberger C ,
Ptchelkine D,
Jones R ,
Desfosses A
Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture.
Kril V ,
Hons M ,
Amadori C,
Zimberger C ,
Couture L,
Bouery Y,
Burlaud-Gaillard J,
Karpov A ,
Ptchelkine D,
Thienel AL ,
Kummerer BM ,
Desfosses A ,
Jones R ,
Roingeard P ,
Meertens L ,
Amara A ,
Reguera J
(2024) Nat Commun , 15 , 8106 - 8106
,
Hons M ,
Amadori C,
Zimberger C ,
Couture L,
Bouery Y,
Burlaud-Gaillard J,
Karpov A ,
Ptchelkine D,
Thienel AL ,
Kummerer BM ,
Desfosses A ,
Jones R ,
Roingeard P ,
Meertens L ,
Amara A ,
Reguera J
(2024) Nat Commun , 15 , 8106 - 8106
Grant Support:
- Agence Nationale de la Recherche (ANR): ANR-22-CE11-0023-01 (France)
- ATIP-Avenir: 2015 (France)