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EMD-17516

Single-particle
2.0 Å
EMD-17516
3D View Gallery
Deposition: 30/05/2023
Map released: 20/03/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17516
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8p73 summary report (pdf.gz) Map and 8p73 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of CAK in complex with inhibitor ICEC0829

EMD-17516

Single-particle
2.0 Å
EMD-17516
3D View Gallery
Deposition: 30/05/2023
Map released: 20/03/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CDK-activating kinase
Fitted models: 8p73

Deposition Authors: Cushing VI , Koh AF , Feng J, Jurgaityte K , Bahl AK, Ali S , Kotecha A , Greber BJ
High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design.
Cushing VI , Koh AF , Feng J, Jurgaityte K , Bondke A, Kroll SHB, Barbazanges M , Scheiper B, Bahl AK, Barrett AGM , Ali S , Kotecha A , Greber BJ
(2024) Nat Commun , 15 , 2265 - 2265
PUBMED: 38480681
DOI: doi:10.1038/s41467-024-46375-9
ISSN: 2041-1723
Grant Support:
  • Medical Research Council (MRC, United Kingdom): MR/V009354/1 (United Kingdom)
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