EMD-17103

Single-particle
2.9 Å
EMD-17103
3D View Gallery
Deposition: 11/04/2023
Map released: 21/02/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17103

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8oq3 summary report (pdf.gz) Map-8oq3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of methylamine treated human complement C3

EMD-17103

Single-particle
2.9 Å
EMD-17103
3D View Gallery
Deposition: 11/04/2023
Map released: 21/02/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: methylamine treated complement C3 in complex with a nanobody enabling dimer formation
Fitted models: 8oq3

Deposition Authors: Gadeberg TAF, Andersen GR
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring.
Gadeberg TAF, Jorgensen MH , Olesen HG, Lorentzen J , Harwood SL, Almeida AV, Fruergaard MU, Jensen RK , Kanis P , Pedersen H, Tranchant E , Petersen SV, Thogersen IB, Kragelund BB , Lyons JA , Enghild JJ , Andersen GR
(2025) Nat Struct Mol Biol
PUBMED: 39849196
DOI: doi:10.1038/s41594-024-01467-4
ISSN: 1545-9985