EMD-16881

Helical reconstruction
2.8 Å
EMD-16881
3D View Gallery
Deposition: 21/03/2023
Map released: 21/02/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16881

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ohi summary report (pdf.gz) Map-8ohi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril

EMD-16881

Helical reconstruction
2.8 Å
EMD-16881
3D View Gallery
Deposition: 21/03/2023
Map released: 21/02/2024
Last modified: 27/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Amyloid fibril form 1a of Tau-PAM4 peptide adducted with the Fmoc protection group
Fitted models: 8ohi

Deposition Authors: Wilkinson M , Louros N , Tsaka G, Ramakers M , Morelli C , Garcia T, Gallardo RU, D'Haeyer S , Goossens V, Audenaert D, Thal DR , Ranson NA , Radford SE , Rousseau F , Schymkowitz J
Local structural preferences in shaping tau amyloid polymorphism.
Louros N , Wilkinson M , Tsaka G, Ramakers M , Morelli C , Garcia T, Gallardo R, D'Haeyer S , Goossens V, Audenaert D, Thal DR , Mackenzie IR, Rademakers R , Ranson NA , Radford SE , Rousseau F , Schymkowitz J
(2024) Nat Commun , 15 , 1028 - 1028
PUBMED: 38310108
DOI: doi:10.1038/s41467-024-45429-2
ISSN: 2041-1723
Grant Support: