EMD-16473

Single-particle
4.41 Å
EMD-16473
3D View Gallery
Deposition: 19/01/2023
Map released: 10/01/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16473

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8c89 summary report (pdf.gz) Map-8c89 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab)

EMD-16473

Single-particle
4.41 Å
EMD-16473
3D View Gallery
Deposition: 19/01/2023
Map released: 10/01/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus
Sample: SARS-CoV-2 Omicron Variant Spike Trimer in complex with three 17T2 Fabs
Fitted models: 8c89

Deposition Authors: Modrego A , Carlero D , Bueno-Carrasco MT , Santiago C , Carolis C , Arranz R , Blanco J , Magri G
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
de Campos-Mata L , Trinite B , Modrego A , Tejedor Vaquero S , Pradenas E , Pons-Grifols A , Rodrigo Melero N, Carlero D , Marfil S, Santiago C , Raich-Regue D , Bueno-Carrasco MT , Tarres-Freixas F, Abanco F, Urrea V , Izquierdo-Useros N , Riveira-Munoz E , Ballana E, Perez M, Vergara-Alert J, Segales J , Carolis C , Arranz R , Blanco J , Magri G
(2024) Nat Commun , 15 , 1051 - 1051
PUBMED: 38316751
DOI: doi:10.1038/s41467-024-45171-9
ISSN: 2041-1723
Grant Support: