EMD-15678

Single-particle
4.6 Å
EMD-15678
3D View Gallery
Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15678

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8avc summary report (pdf.gz) Map-8avc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Mouse leptin:LEP-R complex cryoEM structure (3:3 model)

EMD-15678

Single-particle
4.6 Å
EMD-15678
3D View Gallery
Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Stucture of mouse leptin in complex with a trimerized form of the mouse Lep-R extracellular region
Fitted models: 8avc

Deposition Authors: Verstraete K , Savvides SN , Verschueren KG, Tsirigotaki A
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A, Dansercoer A, Verschueren KHG, Markovic I , Pollmann C , Hafer M, Felix J , Birck C , Van Putte W , Catteeuw D, Tavernier J , Fernando Bazan J, Piehler J , Savvides SN , Verstraete K
(2023) Nat Struct Mol Biol , 30 , 551 - 563
PUBMED: 36959263
DOI: doi:10.1038/s41594-023-00941-9
ISSN: 1545-9985