EMD-15587

Single-particle
2.92 Å
EMD-15587
3D View Gallery
Deposition: 13/08/2022
Map released: 01/03/2023
Last modified: 15/03/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15587

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

BA.4/5 SARS-CoV-2 Spike bound to human ACE2 (three up, full)

EMD-15587

Single-particle
2.92 Å
EMD-15587
3D View Gallery
Deposition: 13/08/2022
Map released: 01/03/2023
Last modified: 15/03/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: BA.4/5 SARS-CoV-2 Spike bound to human ACE2

Deposition Authors: Lau K, Ni D, Beckert B, Nazarov S, Myasnikov A, Pojer F, Stahlberg H, Uchikawa E
Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range
Ni D, Turelli P, Beckert B, Nazarov S, Uchikawa E, Myasnikov A, Pojer F, Trono D, Stahlberg H, Lau K
(2023) PLoS Pathog
DOI: doi:10.1371/journal.ppat.1011206
ISSN: 1553-7374
Grant Support: