EMD-15243

Single-particle
8.59 Å
EMD-15243
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Deposition: 24/06/2022
Map released: 31/05/2023
Last modified: 31/05/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15243
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic ecumicin (class 2)

EMD-15243

Single-particle
8.59 Å
EMD-15243
3D View Gallery
Deposition: 24/06/2022
Map released: 31/05/2023
Last modified: 31/05/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: Mycobacterium tuberculosis ClpC1 bound to the natural product antibiotic Ecumicin

Deposition Authors: Felix J , Fraga H , Gragera M, Bueno T, Weinhaeupl K
Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
Weinhaupl K , Gragera M, Bueno-Carrasco MT , Arranz R , Krandor O, Akopian T, Soares R, Rubin E , Felix J , Fraga H
(2022) J Biol Chem , 298 , 102553 - 102553
PUBMED: 36208775
DOI: doi:10.1016/j.jbc.2022.102553
ISSN: 1083-351X
ASTM: JBCHA3