EMD-15101

Single-particle
3.53 Å
EMD-15101 Deposition: 06/06/2022
Map released: 07/09/2022
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15101

Structure of the DNA-bound FANCD2-FANCI complex containing phosphomimetic FANCI

EMD-15101

Single-particle
3.53 Å
EMD-15101 Deposition: 06/06/2022
Map released: 07/09/2022
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Gallus gallus, synthetic construct
Sample: DNA-bound FANCD2-FANCI that contains phosphomimetic FANCI (S558D, S561D and T567D)
Fitted models: 8a2q

Deposition Authors: Passmore LA , Sijacki T, Alcon P
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination.
Sijacki T, Alcon P , Chen ZA , McLaughlin SH , Shakeel S , Rappsilber J , Passmore LA
(2022) Nat Struct Mol Biol , 29 , 881 - 890
PUBMED: 36050501
DOI: doi:10.1038/s41594-022-00820-9
ISSN: 1545-9985