EMD-15084

Single-particle
3.6 Å
EMD-15084
3D View Gallery
Deposition: 01/06/2022
Map released: 14/06/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15084

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8a1r summary report (pdf.gz) Map-8a1r FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryo-EM structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor

EMD-15084

Single-particle
3.6 Å
EMD-15084
3D View Gallery
Deposition: 01/06/2022
Map released: 14/06/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Schistosoma mansoni
Sample: TGR in complex with an inhibitor
Fitted models: 8a1r

Deposition Authors: Ardini M , Angelucci F , Fata F , Gabriele F, Effantin G , Ling W, Williams DL , Petukhova VZ, Petukhov PA
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
Petukhova VZ, Aboagye SY , Ardini M , Lullo RP , Fata F , Byrne ME, Gabriele F, Martin LM , Harding LNM , Gone V , Dangi B, Lantvit DD, Nikolic D, Ippoliti R , Effantin G , Ling WL , Johnson JJ, Thatcher GRJ, Angelucci F , Williams DL , Petukhov PA
(2023) Nat Commun , 14 , 3737 - 3737
PUBMED: 37349300
DOI: doi:10.1038/s41467-023-39444-y
ISSN: 2041-1723