EMD-15006
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
EMD-15006
Single-particle3.4 Å
Deposition: 20/05/2022Map released: 30/11/2022
Last modified: 24/07/2024
Sample Organism:
Homo sapiens,
Sus scrofa
Sample: Pre-initiation complex of RNA polymerase II with general transcription factors and SNAPc bound to U1 promoter
Fitted models: 7zx7
Deposition Authors: Rengachari S, Schilbach S
,
Kaliyappan T,
Gouge J,
Zumer K ,
Schwarz J,
Urlaub H ,
Dienemann C ,
Vannini A ,
Cramer P
Sample: Pre-initiation complex of RNA polymerase II with general transcription factors and SNAPc bound to U1 promoter
Fitted models: 7zx7
Deposition Authors: Rengachari S, Schilbach S
,
Kaliyappan T,
Gouge J,
Zumer K ,
Schwarz J,
Urlaub H ,
Dienemann C ,
Vannini A ,
Cramer P
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Rengachari S,
Schilbach S ,
Kaliyappan T,
Gouge J,
Zumer K ,
Schwarz J,
Urlaub H ,
Dienemann C ,
Vannini A ,
Cramer P
(2022) Nat Struct Mol Biol , 29 , 1159 - 1169
,
Kaliyappan T,
Gouge J,
Zumer K ,
Schwarz J,
Urlaub H ,
Dienemann C ,
Vannini A ,
Cramer P
(2022) Nat Struct Mol Biol , 29 , 1159 - 1169
Grant Support:
- German Research Foundation (DFG): SFB860 (Germany)
- German Research Foundation (DFG): EXC 2067/1 39072994 (Germany)
- Cancer Research UK: CR-UK C47547/A21536 (United Kingdom)
- Wellcome Trust: 200818/Z/16/Z (United Kingdom)