EMD-14974
Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB, conformation 2
EMD-14974
Single-particle6.75 Å
Deposition: 12/05/2022Map released: 08/02/2023
Last modified: 27/03/2024
Sample Organism:
Mycobacterium tuberculosis H37Rv
Sample: RNA polymerase holoenzyme dimer with sigma factor sigB, conformation 2
Deposition Authors: Brodolin K
Sample: RNA polymerase holoenzyme dimer with sigma factor sigB, conformation 2
Deposition Authors: Brodolin K
Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization.
Morichaud Z
,
Trapani S
,
Vishwakarma RK,
Chaloin L,
Lionne C
,
Lai-Kee-Him J,
Bron P
,
Brodolin K
(2023) Nat Commun , 14 , 484 - 484
,
Trapani S
,
Vishwakarma RK,
Chaloin L,
Lionne C
,
Lai-Kee-Him J,
Bron P
,
Brodolin K
(2023) Nat Commun , 14 , 484 - 484
Secondary citations:
- Morichaud Z, Trapani S, Vishwakarma R, Chaloin L, Lionne C, Lai-Kee-Him J, Bron P & Brodolin K. (2022) Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. bioRxiv,
- Hu Y, Morichaud Z, Perumal AS, Roquet-Baneres F & Brodolin K. (2014) Mycobacterium RbpA cooperates with the stress-response sigma-B subunit of RNA polymerase in promoter DNA unwinding. Nucleic Acids Res, 42, 10399 - 10408
Grant Support:
