EMD-14874

Single-particle
2.54 Å
EMD-14874
3D View Gallery
Deposition: 02/05/2022
Map released: 17/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14874

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7zqs summary report (pdf.gz) Map-7zqs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of Human Transferrin Receptor 1 bound to DNA Aptamer

EMD-14874

Single-particle
2.54 Å
EMD-14874
3D View Gallery
Deposition: 02/05/2022
Map released: 17/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, unidentified
Sample: Human transferrin receptor 1 in complex with DNA aptamer
Fitted models: 7zqs

Deposition Authors: Wang T , Bansia H , Gutierrez D , des Georges A
Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing.
Cheng EL, Cardle II , Kacherovsky N, Bansia H , Wang T , Zhou Y, Raman J , Yen A, Gutierrez D , Salipante SJ, des Georges A , Jensen MC, Pun SH
(2022) J Am Chem Soc , 144 , 13851 - 13864
PUBMED: 35875870
DOI: doi:10.1021/jacs.2c05349
ISSN: 1520-5126
ASTM: JACSAT