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EMD-14068
Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25
EMD-14068
Single-particle2.9 Å
Deposition: 20/12/2021Map released: 13/04/2022
Last modified: 13/11/2024
Sample Organism:
Homo sapiens,
Lama glama
Sample: Human full-length beta3delta GABA(A)R in complex with Nanobody Nb25
Fitted models: 7qn6
Deposition Authors: Sente A
,
Desai R
Sample: Human full-length beta3delta GABA(A)R in complex with Nanobody Nb25
Fitted models: 7qn6
Deposition Authors: Sente A
,
Desai R
Differential assembly diversifies GABA A receptor structures and signalling.
Sente A
,
Desai R,
Naydenova K,
Malinauskas T
,
Jounaidi Y
,
Miehling J,
Zhou X,
Masiulis S,
Hardwick SW
,
Chirgadze DY
,
Miller KW
,
Aricescu AR
(2022) Nature , 604 , 190 - 194
,
Desai R,
Naydenova K,
Malinauskas T
,
Jounaidi Y
,
Miehling J,
Zhou X,
Masiulis S,
Hardwick SW
,
Chirgadze DY
,
Miller KW
,
Aricescu AR
(2022) Nature , 604 , 190 - 194
Grant Support:
- Medical Research Council (MRC, United Kingdom): MR/L009609/1 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/15 (United Kingdom)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 1R01-GM135550 (United Kingdom)
- Wellcome Trust: 206171/Z/17/Z (United Kingdom)
- Wellcome Trust: 202905/Z/16/Z (United Kingdom)
