EMDB EMD-12805

Single particle reconstruction
3.1Å resolution

Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)

Map released:
Last modified:
Overview of EMD-12805
Source organism: Rattus norvegicus [10116]
Fitted atomic model: 7oce
Primary publication:
Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Zhang D, Watson JF, Matthews PM, Cais O, Greger IH
Nature - (2021)
PMID: 34079129

Function and Biology Details

Sample name: GluA1/A2 heterotetramer in complex with auxiliary subunits TARP gamma 8 and CNIH2
Ligands: 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL
Proteins: GluA1/A2 heterotetramer in complex with auxiliary subunits TARP gamma 8 and CNIH2, Glutamate receptor 1, Glutamate receptor 2, Protein cornichon homolog 2, Voltage-dependent calcium channel gamma-8 subunit

Experimental Information Details

Resolution: 3.1Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: OTHER