EMD-12665

Single-particle
3.96 Å
EMD-12665
3D View Gallery
Deposition: 24/03/2021
Map released: 29/09/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12665

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7nzm summary report (pdf.gz) Map-7nzm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I)

EMD-12665

Single-particle
3.96 Å
EMD-12665
3D View Gallery
Deposition: 24/03/2021
Map released: 29/09/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus, Homo sapiens, Bos taurus, Escherichia coli (strain K12)
Sample: pre-dephosphorylation complex of phosphorylated eIF2alpha_2-187 with trapped holophosphatase (PP1A_D64A/PPP1R15A_553-624/G-actin)
Fitted models: 7nzm

Deposition Authors: Yan Y , Hardwick S
Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Yan Y , Harding HP , Ron D
(2021) Nat Struct Mol Biol , 28 , 835 - 846
PUBMED: 34625748
DOI: doi:10.1038/s41594-021-00666-7
ISSN: 1545-9985
Grant Support: