EMDB EMD-12587

Single particle reconstruction
3.6Å resolution

Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab

Map released:
Last modified:
Overview of EMD-12587
Fitted atomic model: 7ntc
Primary publication:
SARS-CoV-2 can recruit a haem metabolite to evade antibody immunity.
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Silva Dos Santos M, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel AG, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjaer S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P
Sci Adv - (2021)
PMID: 33888467

Function and Biology Details

Sample name: Stabilised SARS-CoV-2 spike ectodomain trimer bound to one P008_056 Fab
Ligands: BILIVERDINE IX ALPHA, 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Stabilised SARS-CoV-2 spike ectodomain trimer bound to one P008_056 Fab, Stabilised SARS-CoV-2 spike ectodomain trimer, P008_056 Fab, Spike glycoprotein, P008_056 Fab Heavy chain, P008_056 Fab Light chain

Experimental Information Details

Resolution: 3.6Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)